Réseau Parkinson Québec
3801 rue University H4S 1A8 Montreal, QC, Canada

Research News: Enzyme found that drives neurotoxicity in Alz and Park’s. Blocking action of this enzyme may prevent these conditions from developing through new drug. Researcher Keqiang Ye, Ph.D recently published in Nature: Structural and Molecular Biology a study that found a particular enzyme that is related to the growth of Lewy bodies, which are toxic clumps found in the midbrain and cerebrum and contribute to the development of Parkinson’s. The enzyme, asparagine endope...ptidase of AEP, was found to trim tau (the protein tied to Alzheimer’s) and alpha-synuclein in Parkinsons, to make both proteins more toxic. The hopes with the discovery of this particular enzyme is thus to develop a drug that inhibits AEP. Trials in animal models have already shown that an AEP-inhibiting drug preserves memory and may have a preventative effect against Alzheimer’s diseaseand because of the similar molecular bases in both diseases, Dr Ye and his team are beginning to test AEP-inhibiting drugs in animals with Parkinson’s. https://www.medicalnewstoday.com/articles/318257.php

Ongoing studies at the MNI with the QPN! There are many studies available to participate in if you have been diagnosed with Parkinson Disease. Participation in such studies are key in boosting research and finding future solutions. To find out more, please click the link below. Axis 1: Clinical and Treatment Research ... Axis 2: Non-Motor Symptoms Axis 3: Molecular and Cellular Biology http://rpq-qpn.ca/projets-de-recherche/projets-soutenus/

Mental Health Reminders with the QPN: From the UK Parkinson’s foundation: You are not alone: Parkinson’s is the second most common neurodegenerative disease in North America, and because of that, many support groups and therapies are available. Its okay to ask for help: Reaching out to family and friends for assistance can be very helpful in all cases, whether its motor or mental. ... Get involved: Share your story, fill out questionnaires, participate in research, all of this contributes to a better understanding of Parkinson’s disease.

A new way to create resultsFox Insight! FI is an online clinical study where people with Parkinson's disease and their loved ones share information that could transform the search for better treatments. You can help shape the future of Parkinson's research through completing online studies, a quicker way to find a cure. https://foxinsight.michaeljfox.org/